To prevent problematic interactions between prednisone and other drugs, be sure to tell your doctor if you are allergic to any medications, and what other medications and supplements you are currently taking. You should also inform your doctor if you have or ever had an eye infection, threadworms (a parasite that can live inside the body), diabetes, high blood pressure, emotional problems, myasthenia gravis (a condition of weak muscles), osteoporosis, seizures, liver tumor, liver disease, or kidney disease, if you are pregnant or planning to become pregnant, or if you are breastfeeding.
In addition to the mentioned side effects several others have been reported. In both males and females acne are frequently reported, as well as hypertrophy of sebaceous glands, increased tallow excretion, hair loss, and alopecia. There is some evidence that anabolic steroid abuse may affect the immune system, leading to a decreased effectiveness of the defense system. Steroid use decreases the glucose tolerance, while there is an increase in insulin resistance. These changes mimic Type II diabetes. These changes seem to be reversible after abstention from the drugs.
Radiation therapy attempts to destroy tumor cells by using high-energy radiation focused onto the tumor to destroy the tumor cells' ability to function and replicate. Radiosurgery is a nonsurgical procedure that delivers a single high dose of precisely targeted radiation using highly focused gamma-ray or X-ray beams that converge on the specific area or areas of the brain where the tumor or other abnormality is located, minimizing the amount of radiation to healthy brain tissue. Equipment used to do radiosurgery varies in its radiation source; a gamma knife uses focused gamma rays, and a linear accelerator uses photons, while heavy-charged particle radiosurgery uses a proton beam. Tomotherapy is a type of radiotherapy in which radiation is delivered in a highly precise and individualized manner that minimizes radiation exposure to healthy tissue; it has also been used to treat brain cancer.