Steroid sparing effect

The caudal approach to the epidural space involves the use of a Tuohy needle, an intravenous catheter, or a hypodermic needle to puncture the sacrococcygeal membrane . Injecting local anaesthetic at this level can result in analgesia and/or anaesthesia of the perineum and groin areas. The caudal epidural technique is often used in infants and children undergoing surgery involving the groin, pelvis or lower extremities. In this population, caudal epidural analgesia is usually combined with general anaesthesia since most children do not tolerate surgery when regional anaesthesia is employed as the sole modality.

Noncardioselective beta blockers significantly decrease contractility of the heart and decrease heart rate. Systemic vascular resistance is increased, especially in the muscle and skin. Because these drugs inhibit lipolysis and glycogenolysis, hypoglycemia may occur after intense exercise. In addition, athletes who take beta blockers perceive greater exertion during exercise, which may affect adherence to the prescribed medication regimen. 20 An increased total cholesterol level and a decreased HDL cholesterol level may also be noted. 7

Although epidural steroid injections (also called epidural corticosteroid injections) may be helpful to confirm a diagnosis, they should be used primarily after a specific presumptive diagnosis has been established. Also, injections should not be used in isolation, but rather in conjunction with a program stressing muscle flexibility, strengthening, and functional restoration.
Proper follow-up after injections to assess the patient's treatment response and ability to progress in the rehabilitation program is essential. A limited number of injections can be tried to reduce pain, but careful monitoring of the response is required prior to a second or third injection.

Steroid sparing effect

steroid sparing effect

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